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Pregnancy: There are no studies on the safety of repaglinide in pregnant women, repaglinide should only be used for pregnant women when necessary.
Abnormal blood glucose levels during pregnancy may be associated with an increased incidence of congenital malformations, insulin is recommended as an alternative to repaglinide during pregnancy to maintain optimal blood glucose control.
Lactation: Because of the potential for repaglinide to cause hypoglycemia and possible bone changes in breastfed infants, the drug should be discontinued or breastfeeding should be discontinued, taking into account the importance of the drug to the mother. If repaglinide is discontinued and diet alone is insufficient to control blood glucose, insulin should be used instead.
