Đăng xuất
This drug is contraindicated in the following situations: Hypersensitivity to the active substance or to any of the excipients; history of allergy or asthma triggered by taking this medicine or substances with close activity such as other NSAIDs, acetylsalicylic acid; pregnancy, from the beginning of the 6th month (beyond 24 weeks of amenorrhea); history of gastrointestinal bleeding or perforation during previous treatment with NSAIDs; active peptic ulcer, history of peptic ulcer or recurrent bleeding (2 or more distinct episodes of bleeding or ulceration objectified); severe hepatocellular insufficiency; severe kidney failure; severe heart failure; child under 15 years old.
This medicine should generally not be used in combination with: Oral anticoagulants, other NSAIDs (including salicylates from 3 g/day in adults); heparin; lithium; methotrexate from 20 mg/week, pemetrexed.
