Pregnancy: During pregnancy, especially in the first 3 months, baclofen should only be employed if its use is of vital necessity. The benefits of the treatment for the mother must be carefully weighed against the possible risks for the child. Baclofen crosses the placental barrier.
Foetal/neonatal adverse reactions: Withdrawal reactions including postnatal seizures in infants have been documented after intrauterine exposure to oral baclofen.
Lactation: In mothers taking baclofen in therapeutic doses, the active substance passes into the breast milk, but in quantities so small that no undesirable effects on the infant are to be expected.