Should nausea persist following a reduction in dosage, it is recommended that baclofen be ingested with food or a milk beverage.
Lowering of the convulsion threshold and convulsions may occur, particularly in epileptic patients.
In patients with a history of psychiatric illness or with cerebrovascular disorders (e.g. stroke) as well as in elderly patients, adverse reactions may assume a more serious form.
Certain patients have shown increased spasticity as a paradoxical reaction to the medication.
An undesirable degree of muscular hypotonia - making it more difficult for patients to walk or fend for themselves - may occur and can usually be relieved by re-adjusting the dosage (i.e. by reducing the doses given during the day and possibly increasing the evening dose).
The following terms and frequencies have been used: Very common: R ≥1/10; Common: 1/10 > R ≥1/100; Uncommon: 1/100 > R ≥1/1000; Rare: 1/1000 > R ≥1/10,000; Very rare: R <1/10,000; Unknown: When it is not possible to estimate from the available data. (See table.)

Immediately notify the doctor or pharmacist of any adverse reactions encountered when using the drug.
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