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Pregnancy: Pregnancy Category C: Reproduction studies have been performed in rats and mice at doses up to 16 times the usual daily human dose and have revealed no evidence of impaired fertility or harm to the fetus due to Ciprofloxacin. In rabbits, Ciprofloxacin produced gastrointestinal disturbances resulting in maternal weight loss and an increased incidence of abortion. No teratogenicity was observed. After intravenous administration of doses up to 20 mg/kg, no maternal toxicity was produced, and no embryo-toxicity or teratogenicity was observed.
Nursing Mothers: Ciprofloxacin is excreted in human milk. Because of the potential for serious adverse reactions in infants nursing from mothers taking Ciprofloxacin, a decision should be made either to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
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