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Ciprofloxacin is indicated for the treatment of infections caused by susceptible strains of the designated microorganisms in the conditions listed as follows:
Urinary Tract Infections: Caused by Escherichia coli, Klebsiella pneumoniae, subspecies pneumoniae, Enterobacter cloacae, Serratia marcescens, Proteus mirabilis, Providencia rettgeri, Morganella morganii, Citrobacter diversus, Citrobacter freundii, Pseudomonas aeruginosa, Staphylococcus epidermis and Enterococcus faecalis.
The treatment of mild to moderate lower respiratory tract infections, skin and skin structure infections and bone and joint infections due to the organisms listed in each section as follows. In severe and complicated lower respiratory tract infections, safety and effectiveness of the IV formulation have not been established.
Lower Respiratory Infections: Caused by Eschericia coli, Klebsiella pneumoniae subspecies pneumoniae, Enterobacter cloacae, Proteus mirabilis, Pseudomonas aeruginosa, Haemophilus influenzae, Haemophilus parainfluenzae, and Streptococcus pneumoniae.
Skin and Skin Structural Infections: Mild to moderate infections caused by Eschericia coli, Klebsiella pneumoniae subspecies pneumoniae, Enterobacter cloacae, Proteus mirabilis, Proteus vulgaris, Providencia stuartii, Morganella morganii, Citrobacter freundii, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermis, and Streptococcus pyogenes.
Bone and Joint Infections: Mild to moderate infections caused by Enterobacter cloacae, Serratia marcescens, and Pseudomonas aeruginosa.
Gastrointestinal Infections: Caused by resistant gram-negative organisms with appropriate therapy for anaerobic organisms.
Septicemia, Endocarditis: From gram negative-resistant pathogen members; endocarditis from Q fever (Coxiella burnetii).
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