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Use in Pregnant women: The data that are available on administration of ciprofloxacin to pregnant women indicates no malformative or feto/neonatal toxicity of ciprofloxacin. Animal studies do not indicate direct or indirect harmful effects with respect to the reproductive toxicity. In juvenile and prenatal animal exposed to quinolones, effects on immature cartilage have been observed, thus, it cannot be excluded that the drug could cause damage to articular cartilage in human immature organism/fetus.
As precautionary measure, it is preferable to avoid the use of ciprofloxacin during pregnancy.
Use in Lactating mothers: Ciprofloxacin is excreted in breast milk. It should be used in caution when given to breast feeding mothers as this was found to cause arthropathy in young animals. (See Contraindications.)
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