Ciprofloxacin hydrochloride is given orally to adults 18 years of age and older in doses 500 mg twice per day every 12 hours.
For the treatment of uncomplicated acute gonorrhea, oral ciprofloxacin 250 mg as single dose is recommended.
For meningococcal meningitis prophylaxis, 500 mg oral ciprofloxacin is given.
Ciprofloxacin 15 mg/kg twice per day, not to exceed 500 mg twice per day, may be given for children and adolescents for inhalation of anthrax for 60 days.
Or as prescribed by the physician.
Patients with renal impairment are given reduced doses with regular monitoring of the plasma concentrations of the drug. If creatinine clearance is <20 mL per minute, 250 mg oral ciprofloxacin is administered.
                                
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