Patients who drive and operate machines musts not take ciprofloxacin with alcohol.
The risk of crystalluria is high in patients with alkaline urine.
Use in Patients with renal impairment: Ciprofloxacin should be used with caution in patients with severe renal impairment (see Dosage & Administration).
Use in Patients with hepatic impairment: Ciprofloxacin should be used with caution in patients with severe hepatic impairment where peak plasma concentration and serum half-life may be increased.
Use in Pregnancy & Lactation: See USE IN PREGNANCY & LACTATION section for further information.
Use in the Elderly: Dose of ciprofloxacin should be reduced in the elderly as increased bioavailability and reduced renal clearance were seen probably due to absorption or first pass elimination.
                                
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