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Pregnancy: Category C.
Alendronate has not been studied in pregnant women. Although no data exist on fetal risk in humans, bisphosphonates are incorporated into the bone matrix and is gradually released over a period of years. This may theoretically cause serious skeletal malformation when a fetus is exposed to alendronate. Alendronate should not be used during pregnancy.
Lactation: It is not known whether alendronate is excreted in human milk. Alendronate should not be used by breastfeeding women.
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