Alendra Dosage/Direction for Use

Treatment of Osteoporosis in Postmenopausal Women and in Men: Recommended Dosage: Orally, 70 mg once a week.
Or, as prescribed by a physician.
Prevention of Postmenopausal Osteoporosis: Recommended Dosage: Orally, 35 mg once a week.
Or, as prescribed by a physician.
Administration Instructions: Take alendronate with plain water only at least 30 minutes before the first food, beverage or medication of the day. Alendronate's absorption will likely be reduced when taken with other beverages (including mineral water), food and some medications. Taking alendronate less than 30 minutes after other medications, food and beverages other than plain water will decrease its absorption and lessen its effect.
Alendronate should only be taken upon arising for the day. It should not be taken at bedtime or before getting up for the day.
Always swallow alendronate with a full glass of water (6 to 8 oz; 180 to 240 mL) to facilitate delivery to the stomach and thus avoid the risk of esophageal irritation.
Do not chew or suck the tablet to avoid oropharyngeal ulceration. Do not lie down within the next 30 minutes and until after the first food of the day.
The patient should follow these instructions to decrease the risk of esophageal adverse events.
Supplemental calcium and vitamin D may be necessary if dietary intake is inadequate. However, patients must wait at least 30 minutes after taking alendronate before taking any other oral medications.
Information on Missed Dose: When a dose is missed, alendronate 70 mg once-weekly tablet should be taken on the morning after the patient remembers. Do not take two doses on the same day. Return to once a week dosing as originally scheduled on the patient's chosen day.