Specific information on acute alendronate overdosage is not available. However, hypocalcemia, hypophosphatemia and upper gastrointestinal adverse events (e.g., upset stomach, heartburn, esophagitis, gastritis, or ulcer) may result from oral overdosage.
Give milk or antacids to bind alendronate. Do not induce vomiting and keep the patient in an upright position to avoid esophageal irritation.
Dialysis is not beneficial and is therefore not recommended.
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