Pongesic Overdosage

Symptoms: Extended effect of the adverse reactions. Gastrointestinal haemorrhage, acute renal failure, convulsions, coma and hypoprothrombinaemia have been reported following overdose.
Treatment: Empty the stomach via induction of emesis (in alert patients only) or gastric lavage. Syrup of ipecac may induce symptoms similar to those of NSAID toxicity, which may complicate diagnosis, and therefore, not recommended for induction of emesis.
Administering activated charcoal.
Monitoring and supporting vital functions.
Instituting symptomatic and other supportive treatment.
Administering as required plasma volume expanders for severe hypotension, diazepam (5 to 10 mg for adults or 0.1 to 0.3 mg per kg bodyweight for children) or other appropriate benzodiazepine anticonvulsant for convulsions; Vitamin K1 (10 to 20 mg intravenously) for hypoprothrombinaemia, and/or dopamine (2.5 mcg per kg bodyweight per minute) plus dobutamine (5 to 40 mcg per kg bodyweight per minute) intravenously, to prevent or reverse early indications of renal failure.