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Headache, drowsiness, dizziness, nervousness, and visual disturbances have been reported. There may be hypersensitivity reactions including skin rashes and urticaria, and occasionally allergic glomerulonephritis; asthma may be precipitated.
Reported haematological effects include haemolytic anaemia, agranulocytosis, pancytopenia, thrombocytopenia or thrombocytopenic purpura and bone marrow aplasia. Renal failure, glomerulonephritis and papillary necrosis have been reported. Therapy should be discontinued if diarrhoea or skin rash occur.
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