Pongesic: Dosing, Side Effect & Interaction

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Warnings Special Precautions Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Mefenamic acid

Indications/Uses

Relief of mild to moderate pain including headache, dental pain, post-op & postpartum pain, & dysmenorrhoea; musculoskeletal & joint disorders eg, OA & RA; menorrhagia.

Click to view Pongesic detailed prescribing information

Dosage/Direction for Use

Adult Initially 500 mg, followed by 250 mg every 6 hr as needed, for no longer than 7 days at a time.

Click to view Pongesic detailed prescribing information

Overdosage

View Pongesic overdosage for action to be taken in the event of an overdose.

Administration

Should be taken with food: Take w/ or immediately after meals.

Contraindications

Hypersensitivity including asthma, urticaria, rhinitis. Active peptic ulceration. Inflammatory bowel disease. Pregnancy & lactation.

Click to view Pongesic detailed prescribing information

Warnings

For additional cautionary notes to warn of the potential risk of using the medicine... Click to view Pongesic detailed prescribing information

Special Precautions

Risk of GI ulceration, bleeding, & perforation; increased risk in patients w/ history of serious GI events & other risk factors associated w/ PUD (eg, alcoholism, smoking, & corticosteroid therapy). Should not be co-administered w/ other NSAIDs. Caution in the elderly, in patients w/ bronchospasm, bleeding disorders, CV disease, & in liver or kidney failure. Greater risk of renal dysfunction due to NSAID-induced inhibition of renal prostaglandin synthesis in patients w/ CHF, cirrhosis, diuretic-induced vol depletion, or renal insufficiency. Discontinue therapy in patients who develop diarrhoea or rash. Safety & efficacy have not been established in childn ≤14 yr.

Click to view Pongesic detailed prescribing information

Adverse Reactions

GI disturbances including diarrhoea, nausea, vomiting, & abdominal pain.

Click to view Pongesic detailed prescribing information

Drug Interactions

Enhanced effects of oral anticoagulants, phenytoin, & sulphonylurea antidiabetics. Increased plasma conc of lithium, MTX, & cardiac glycosides. Increased risk of nephrotoxicity w/ ACE inhibitors, cyclosporine, or diuretics. Increased risk of hyperkalaemia w/ ACE inhibitors & K-sparing diuretics. Reduced antihypertensive effects of some antihypertensive agents including ACE inhibitors, β-blockers, & diuretics. Risk of convulsions w/ quinolones. Increased risk of adverse effects w/ concomitant use of >1 NSAID. Increased risk of GI bleeding & ulceration w/ corticosteroids. Some NSAIDs can interfere w/ thyroid function tests by lowering serum thyroid hormone conc.

Click to view Pongesic detailed prescribing information

Storage

View Pongesic storage conditions for details to ensure optimal shelf-life.

Description

View Pongesic description for details of the chemical structure and excipients (inactive components).

Action

View Pongesic mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

ATC Classification

M01AG01 - mefenamic acid ; Belongs to the class of non-steroidal antiinflammatory and antirheumatic products, fenamates.

Regulatory Classification

P₁S₁S₃

Presentation/Packing

Form

Pongesic FC tab 250 mg

Packing/Price

1000's

Pongesic

mefenamic acid

Manufacturer:

Pharmaniaga

Distributor:

HealthCare PharmaScience