Đăng xuất
If there is a high fever, treatment must be discontinued, as this sign may be one of the factors of "neurotic drug malignancy syndrome".
Special Warnings and Precautions for Use: Caution must be exercised when taking sulpiride, as the drug can cause neuroleptic malignancy. During treatment, if the patient sees an unexplained high fever, the drug must be stopped immediately because high fever can be a manifestation of neuroleptic malignancy.
Sulpirides prolong the QT interval, depending on the dose. This effect increases the risk of severe arrhythmias, especially torsion, especially when there is a slow heart rate < 55 beats/minute, hypokalemia, congenital or acquired long QT interval (due to combination with another drug increases the QT interval). Before taking sulpiride, if possible, the previously mentioned factors must be excluded, an additional ECG should be done.
Caution must be exercised when using sulpirides for the elderly, especially when suffering from dementia, when there are risk factors for cerebrovascular accidents because of susceptibility to orthostatic hypotension, easy falls, drowsiness, and extrapyramidal effects. The risk of death is usually increased with the use of antipsychotics at this age.
Blood glucose monitoring for people with diabetes or at risk of diabetes must be monitored at the start of sulpride therapy.
In cases of renal failure, the dose of sulpiride should be reduced and monitoring should be increased. If kidney failure is severe, intermittent treatment should be given.
It is necessary to strengthen the monitoring of the following subjects: People with epilepsy because they are likely to have a lowered seizure threshold.
People who drink alcohol or take alcohol-containing drugs do so because it increases drowsiness.
People with mild mania, low-dose sulpirides can cause severe symptoms.
Effects on Ability to Drive and Use Machines: The drug can cause drowsiness, so caution should be exercised for drivers or machinery operators.
