Sign Out
Adult: Negative symptoms of schizophrenia: Start by taking 200-400 mg/time, twice daily, if necessary, the maximum dose can be increased to 800 mg/day.
Positive symptoms of schizophrenia: 400 mg/time, twice daily. Gradually increase the dose to a maximum of 1200 mg/time, twice daily.
Combined negative and positive symptoms: 400-600 mg/time, twice daily.
Children: Children over 14 years old: Take 3-5 mg/kg/day.
Children under 14 years old: No indication.
Elderly: The dose for the elderly is the same as for adults, but the initial dose is always low and then gradually increased.
Start 50-100 mg/time, twice daily, then gradually increase to an effective dose.
Renal impairment: The dose must be reduced or the interval between doses must be increased depending on creatinine clearance.
Creatinine clearance 30-60 mL/min: The dose is 2/3 of the normal dose.
Creatinine clearance 10-30 mL/min: Take a dose equal to 1/2 of the normal dose.
Clearance less than 10 mL/min: Take a dose equal to 1/3 of the normal dose.
Or it is possible to increase the gap between doses by 1.5; 2 and 3 times more than normal.
However, in cases of moderate to severe renal impairment, sulpiride should not be used, if possible.
