Sanacore Dosage/Direction for Use

General: Sanacore is intended for hospital use only with monitoring and cardiorespiratory resuscitation equipment available for immediate use. It should be administered by rapid IV bolus injection according to the ascending dosage schedule as follows. To be certain the solution reaches the systemic circulation administer either directly into a vein or into an IV line. If given into an IV line it should be injected as proximally as possible, and followed by a rapid saline flush.
Sanacore should only be used when facilities exist for cardiac monitoring. Patients who develop high-level AV block at a particular dose should not be given further dosage increments.
Therapeutic dose: Adult: Initial dose: 3 mg given as a rapid intravenous bolus (over 2 seconds).
Second dose: If the first dose does not result in elimination of the supraventricular tachycardia within 1 to 2 minutes, 6 mg should be given also as a rapid intravenous bolus.
Third dose: If the second dose does not result in elimination of the supraventricular tachycardia within 1 to 2 minutes. 12 mg should be given also as a rapid intravenous bolus.
Additional or higher doses are not recommended.
Children: No controlled paediatric studies have been performed. The level of evidence does not allow a recommended posology.
The safety and efficacy of adenosine in children aged 0 to 18 years have not been established.
Elderly: See dosage recommendations for adults.
Diagnostic dose: The previously mentioned ascending dosage schedule should be employed until sufficient diagnostic information has been obtained.
Method of administration: Rapid intravenous injection only.