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Use in pregnancy: The safety of ketorolac tromethamine during human pregnancy has not been established.
In view of the known effects of NSAIDs on the fetal cardiovascular system (risk of closure of the ductus arteriosus) and on uterine contraction, ketorolac is contraindicated during pregnancy, labor, or delivery.
Use in lactation: Ketorolac and its metabolites have been shown to pass into the fetus and milk of animals. Ketorolac has been detected in human milk at low concentrations; therefore, ketorolac is contraindicated in mothers who are breastfeeding.
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