Pregnancy: Category C.
Adverse events were observed in animal reproduction studies. In addition, male-mediated teratogenicity has been observed in animal reproduction studies; implications in humans are not defined. Impaired male and female fertility have been noted in animal studies.
Lactation: Pregabalin is excreted in the milk of lactating women (see Pharmacology: Pharmacokinetics: Breastfeeding Women under Actions). As the safety of pregabalin in infants is not known, breastfeeding is not recommended during treatment with pregabalin. A decision must be made whether to discontinue breastfeeding or to discontinue from pregabalin therapy taking into account the benefit of breastfeeding for the child and the benefit of therapy for the woman.
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