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According to Notification of the Ministry of Public Health: Avoid usage in patient with moderate to severe hepatic impairment.
Avoid usage in patient with QT prolongation and with a history of QT prolongation and on patient with concomitant use of drug-induced QT prolongation such as cisapride, erythromycin and ketoconazole.
Avoid usage in patient with hypokalemia and hypomagnesemia.
Avoid concomitant usage with CYP3A4 inhibitors such as ketoconazole, erythromycin, cimetidine and omeprazole, due to the elevation of plasma domperidone.
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