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Safe use of the medicine during pregnancy has not been established; therefore it should be used during pregnancy only when the potential benefit justifies the possible risks to the fetus.
Low concentrations of Domperidone are found in the breast milk, but the long-term potential for adverse effects in the nursing infant have not been determined. Therefore it is not recommended in nursing mothers including to increase milk production, due to the unknown risks to the nursing infant. A decision should be made whether to discontinue nursing or the drug.
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