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Pregnancy: Category C.
Adverse events have been observed in animal reproduction studies. Levetiracetam crosses the placenta and can be detected in the neonate at birth. Concentrations in the umbilical cord at delivery are similar to those in the maternal plasma. Serum concentrations of levetiracetam may be decreased as pregnancy progress; monitor carefully throughout pregnancy and postpartum.
Lactation: Levetiracetam is distributed into milk. Because of the potential for serious adverse reactions to levetiracetam in nursing infants, a decision should be made whether to discontinue nursing or the drug, taking into account the importance of the drug to the woman.
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