Sign Out
Symptom and signs: somnolence, agitation, aggression, depressed level of consciousness, respiratory depression and coma were observed with levetiracetam overdoses.
Treatment: There is no specific antidote for levetiracetam. Treatment of an overdose will be symptomatic and may include heamodialysis. The dialyser extraction efficiency is 60% for levetiracetam and 74% for the primary metabolite. Further management should be as clinically indicated or as recommended by the national poisons centre, where available.
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