Chalocaine Viscous Solution Adverse Reactions

Systemic adverse reactions may result from high plasma levels caused by excessive dosage or rapid absorption, or may result from a hypersensitivity, idiosyncrasy or reduced tolerance on the part of the patient. The systemic effects mainly involves the central nervous system and the cardiovascular system.
Central Nervous System: CNS reactions are excitatory and/or depressant and may be characterised by restlessness, excitement, nervousness, paraesthesias, dizziness, tinnitus, blurred vision, nausea and vomiting. Numbness of the tongue, lightheadedness followed by sedation. Excitation when it occurs maybe transient or followed by depression with drowsiness, respiratory failure and coma.
Cardiovascular System: Cardiovascular reactions are usually depressant and may be characterized by hypotension, bradycardia, arrhythmias and possibly cardiac arrest.
Allergic reactions: Allergic reactions may occur as a result of sensitivity either to the local anesthetic agent or to other ingredients in the formulation. Allergic reactions as a result of sensitivity to lignocaine are rare. Allergic reactions are characterized by cutaneous lesions, urticarial, edema or anaphylactoid reaction.