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Apreszine 25: Hypersensitivity to hydralazine; coronary artery disease; mitral valvular rheumatic heart disease.
Hydralazine is contraindicated in patients with severe tachycardia, dissecting aortic aneurysm, heart failure with high cardiac output, cor pulmonale, or myocardial insufficiency due to mechanical obstruction, for example aortic or mitral stenosis or constrictive.
Hydralazine is also contraindicated in patients with idiopathic systemic lupus erythematosus (SLE) and related disorders.
Apreszine 50: Hydralazine is contraindicated in patients with: Hypersensitivity to the active substance, dihydralazine or to any of the excipients listed in Description.
Idiopathic systemic lupus erythematosus (SLE) and related diseases.
Severe tachycardia.
High output cardiac failure (e.g. in thyrotoxicosis).
Myocardial insufficiency due to mechanical obstruction (e.g. in the presence of mitral or aortic stenosis or constrictive pericarditis).
Cor pulmonale.
Dissecting aortic aneurysm.
Porphyria.
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