Sinuzerc Special Precautions

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Contraindications Warnings Special Precautions Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Full Prescribing Info

Special Precautions

Patients with hepatic impairment or renal insufficiency (e.g. glomerular filtration rate less than 30 mL/min), including geriatric patients, have decreased clearance of the drug, and should be given a lower initial dose of loratadine. Because patients with hepatic impairment experience greater decreases in clearance of loratadine than pseudoephedrine, and the doses of loratadine than pseudoephedrine in the fixed-combination preparations cannot be individually adjusted, these preparations generally should not be used in patients with hepatic insufficiency. Patients with renal insufficiency should receive a lower initial dosage of the fixed-combination preparations.

loratadine

Manufacturer:

Flamingo

Distributor:

Trumed