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Pregnancy: Several studies on animals with fosfomycin trometamol have not shown any evidence of damaging effects on the fetus. Previous studies in rats, sodium and calcium fosfomycin we could only detect toxic effects on fetus when using 25 times therapeutic dose. In rabbits the minimum dose doesn't show toxicity signs.
In spite of results of studies on animals with fosfomycin trometamol have not shown any teratogenic effect, and single dose administration in pregnancy reduce teratogenic risk compared with longer treatments, the administration is only recommended when the benefit/ risk balance is considered favourable.
Breastfeeding: Fosfomycin trometamol is excreted into milk during breastfeeding, in consequence, the administration is only recommended in breastfeeding when the benefit/risk balance is considered favourable.
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