Exelfos Special Precautions

Hypersensitivity reactions, including anaphylaxis and anaphylactic shock, may occur during fosfomycin treatment and may be life-threatening (see Adverse Reactions). If such reaction occurs, fosfomycin should never be re-administrated and an adequate medical treatment is required. Before administering Fosfomycin (Exelfos), it is advisable to ask the patient about any previous manifestations of hypersensitivity to fosfomycin.
Clinical symptoms generally disappear in 2 or 3 days after treatment. The occasional persistence of some symptoms does not mean a therapeutic failure, it could probably be a consequence of the inflammation process.
Food delays oral absorption of fosfomycin trometamol, as consequence, fosfomycin trometamol administration is recommended on an empty stomach, 1 hour before of food ingestion or 2 hours after food ingestion.
Fosfomycin (Exelfos) contains sucrose. It is not recommended in patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency.
Effects on ability to drive and use machines: Not relevant.