Dalman Use In Pregnancy & Lactation

Pregnancy: Pregnancy category is C.
Women with childbearing potential/Contraception: Studies on animals are insufficient in terms of the effects on pregnancy or embryonal/fetal development and/or postnatal and/or postnatal development. The potential risk for humans is unknown.
Pregnancy Period: There are insufficient data regarding its safety in human pregnancy. In animal reproduction studies, adverse effects typical of potent corticosteroids were seen only at high systemic exposure levels; direct intranasal administration provides minimal systemic exposure.
As with other drugs, the benefits of intranasal fluticasone propionate use during pregnancy and lactation should outweigh the possible risks that may arise from using the product or alternative treatment methods.
Lactation Period: It has not been studied whether fluticasone propionate is excreted in breast milk. In lactating laboratory rats, fluticasone propionate was seen in milk when measurable plasma levels were achieved following subcutaneous administration. However, plasma levels are low following intranasal administration of fluticasone propionate at recommended doses.