Clindal/Clindal Injection Special Precautions

Patients with impaired hepatic and renal function.
Since clindamycin is reported to possess neuromuscular-blocking activity, it should be used with care with other drugs having similar activity.
Caution should be used when prescribing Clindamycin to individuals with a history of gastrointestinal disease, especially colitis.
Periodic liver and kidney function tests should be carried out during prolonged therapy. Such monitoring is also recommended in neonates and infants.
The dosage of Clindamycin may require reduction in patients with renal or hepatic impairment due to prolongation of the serum half-life.
Prolonged administration of Clindamycin, as with any anti-infective, may result in super-infection due to organisms resistant to clindamycin.
Care should be observed in the use of Clindamycin in atopic individuals.
Precautions During Application: Because esophagus ulcer may occur if this drug stays and disintegrates in esophagus, administer with water or milk and be careful to administer this drug right before sleep.