Anpheclor Special Precautions

Chloramphenicol (Ampheclor) is contraindicated in patients with a history of hypersensitivity or toxic reaction to the drug. It should never be given for minor infections or for prophylaxis. Repeated courses and prolonged treatment should be avoided. Routine periodic Blood examinations are advisable in all patients, but will not warm of aplastic anemia.
Because of the risk of the grey syndrome, newborn infants should never be given Chloramphenicol (Anpheclor). Unless it may be life saving and there is no alternative treatment. The use of chloramphenicol (Anpheclor) is probably best avoided during pregnancy and in nursing mothers since chloramphenicol (Anpheclor) given to the mother is excreted in the milk.
Concomitant administration of chloramphenicol with other drugs liable to depress bone marrow function should be avoided.