HuCog Dosage/Direction for Use

Dosage in the female: Ovulation induction in subfertility due to anovulation or impaired follicle ripening: Usually, one injection of 5,000-10,000 I.U. HuCoG to complete treatment with an FSH-containing preparation. Preparation of follicles for puncture in controlled ovarian hyperstimulation programs: Usually, one injection of 5,000-10,000 I.U. HuCoG to complete treatment with an FSH-containing preparation. Luteal phase support: Two to three repeat injections of 1,000 to 3,000 I.U. may be given within 9 days following ovulation or embryo transfer (for example on day 3, 6 and 9 after ovulation induction).
Dosage in the male: Hypogonadotropic hypogonadism: 1,000-2,000 I.U. HuCoG two to three times per week. If the main complaint is subfertility, (HCG) may be given with an additional follitropin (FSH)-containing preparation two to three times a week. This treatment should be continued for at least three months before any improvement in spermatogenesis can be expected.
During this treatment testosterone replacement therapy should be suspended. Once achieved, the improvement may sometimes be maintained by (HCG) alone. Delayed puberty associated with insufficient gonadotropic pituitary function: 1,500 I.U. two to three times weekly for at least six months. Cryptorchidism, not due to anatomical obstruction: Under 2 years of age: 250 I.U. twice weekly for six weeks, Under 6 years of age: 500-1,000 I.U. twice weekly for six weeks, Over 6 years of age: 1,500 I.U. twice weekly for six weeks. If necessary, this treatment can be repeated.
Reconstitution Instruction: Reconstitute the contents of vial containing HuCoG in 1ml of Sodium Chloride Injection BP and administer subcutaneous/intramuscular immediately.
Route of Administration: Intramuscular (IM) + Subcutaneous (SC).