Bravigo Drug Interactions

Patients must be advised to inform the doctor or pharmacist if they are taking, have recently taken or might take any other medicines.
Make sure to advise the patients to inform the doctor if they are taking any of the following medicines, as a dose adjustment of Bravigo or monitoring should be required: fluconazole (an antifungal medicine); rifampicin (an antibiotic); barbiturates (for difficult sleeping or epilepsy); phenytoin (for epilepsy); Hypericum perforatum or St John's Wort (herbal treatment for depression); QT prolonging medicines to treat either heart rhythm disorders or other conditions; quinidine, disopyramide, ibutilide, sotalol, amiodarone (to treat heart rhythm disorders); bepridil (to treat angina pectoris); certain types of medicines to treat anxiety, schizophrenia or other psychoses (such as pimozide, ziprasidone, sertindole); anti-malarial medicines (such as mefloquine or halofantrine); intravenous erythromycin (an antibiotic); pentamidine (an antiparasitic medicine); cisapride (against the gastro-oesophageal reflux); some types of diuretics which may cause decrease in blood potassium level, such as furosemide, hydrochlorothiazide, indapamide (used to treat oedema, high blood pressure).
Bravigo with food and drink: Ivabradine exposure was increased by 2-fold following the co-administration with grapefruit juice. Therefore, the intake of grapefruit juice should be avoided.