Bravigo Dosage/Direction for Use

Always take this medicine exactly as prescribed. Patients must be advised to check with the doctor or pharmacist if they are not sure.
Bravigo should be taken during meals.
Bravigo 5 mg tablet can be divided into equal doses.
Treatment for stable angina pectoris: It is recommended that the decision to initiate or titrate treatment takes place with the availability of serial heart rate measurements, ECG or ambulatory 24-hour monitoring. The starting dose of ivabradine should not exceed 5 mg twice daily in patients aged below 75 years. If the patient still has angina symptoms and has tolerated the 5 mg twice daily dose well, the dose may be increased. The maintenance dose should not exceed 7.5 mg twice daily. The doctor will prescribe the right dose. The usual dose is one tablet in the morning and one tablet in the evening. In some cases (e.g. if patient is aged 75 years or more), half the dose may be prescribed i.e., one half 5 mg tablet of Bravigo 5 mg (corresponding to 2.5 mg ivabradine) in the morning and one half 5 mg tablet in the evening. If there is no improvement in symptoms of angina within 3 months after start of treatment, treatment of ivabradine should be discontinued.
In addition, discontinuation of treatment should be considered if there is only limited symptomatic response and when there is no clinically relevant reduction in resting heart rate within three months. If, during treatment, heart rate decreases below 50 beats per minute (bpm) at rest or the patient experiences symptoms related to bradycardia such as dizziness, fatigue or hypotension, the dose must be titrated downward including the lowest dose of 2.5 mg twice daily. After dose reduction, heart rate should be monitored. Treatment must be discontinued if heart rate remains below 50 bpm or symptoms of bradycardia persist despite dose reduction.
Treatment for chronic heart failure: The usual recommended starting dose is one tablet of Bravigo 5 mg twice daily increasing if necessary to one tablet of Bravigo 7.5 mg twice daily. The doctor will decide the right dose. The usual dose is one tablet in the morning and one tablet in the evening. In some cases (e.g. if patient is aged 75 years or more), half the dose may be prescribed i.e., one half 5 mg tablet of Bravigo 5 mg (corresponding to 2.5 mg ivabradine) in the morning and one half 5 mg tablet in the evening.
Forgotten intake of Bravigo: If the patient forgets to take a dose of Bravigo, the next dose should be taken at the usual time. A double dose should not be taken to make up for the forgotten dose.
Stopping intake of Bravigo: As the treatment for angina or chronic heart failure is usually life-long, patients must be advised to discuss with the doctor before stopping this medicinal product.
If the effect of Bravigo is too strong or too weak, patients must be advised to talk to the doctor or pharmacist.
Patients must be advised if they have any further questions on the use of this medicine.