Bravigo should not be taken: if the patient is allergic to ivabradine or any of the other ingredients of this medicine (listed in Description ); if the patient's resting heart rate before treatment is too slow (below 70 beats per minute); if the patient is suffering from cardiogenic shock (a heart condition treated in hospital); if the patient suffers from a heart rhythm disorder (sick sinus syndrome, sino-atrial block, AV-block of 3rd degree); if the patient is having a heart attack; if the patient suffers from very low blood pressure; if the patient suffers from unstable angina (a severe form in which chest pain occurs very frequently and with or without exertion); if the patient has heart failure which has recently become worse; if the patient's heartbeat is exclusively imposed by a pacemaker; if the patient suffers from severe liver problems; if the patient is already taking medicines for the treatment of fungal infections (such as ketoconazole, itraconazole), macrolide antibiotics (such as josamycin, clarithromycin, telithromycin or erythromycin given orally), medicines to treat HIV infections (such as nelfinavir, ritonavir) or nefazodone (medicine to treat depression) or heart rate reducing calcium channel blockers such as verapamil or diltiazem (used for high blood pressure or angina pectoris); if the patient is a woman able to have children and not using reliable contraception; if the patient is pregnant or trying to become pregnant; if the patient is breast-feeding.