There are no well-controlled or adequate studies on pregnant women. After spraying the maximum clinically recommended dose for the patient, the plasma mometasone concentration was not measured, so the fetal exposure to the drug was considered negligible and the possibility of reproductive toxicity was very low.
As with other nasal corticosteroid preparations, Brusonex should only be given to pregnant, lactating women of reproductive age when the benefits may outweigh the potential risks to the mother, fetus and young child. Children whose mothers take corticosteroids during pregnancy must be closely monitored for adrenal insufficiency.