Corticosteroids can cause hyperadrenal cortical hyperplasia or inhibition of the hypothalamic-pituitary-adrenal axis (HPA), especially in young children or patients who take high doses over a prolonged period of time. Inhibition of the HPA axis can lead to adrenal insufficiency.
Adrenal suppression may occur in some patients treated with high doses of mometasone furoate spray for prolonged treatment of asthma. Systemic absorption may occur after nasal spray, especially after high doses or prolonged periods of time.
Mometasone furoate spray can aggravate pre-existing diseases such as tuberculosis, bacterial infections, superbugs, fungi or parasites, or eye herpes. Chickenpox or measles can progress more severely or even cause death in susceptible patients.
Avoid nasal corticosteroids in patients who have recently had nasal wall ulcers, or who have recently had rhinoplasty or nasal injury.
Corticosteroids sprayed through the mouth and nasal spray for a long time can cause a decrease in the mineral density of bones and cause a large rate decrease in pediatric patients. These therapies can also cause glaucoma and/or subcapsular cataracts. To minimize the systemic effects of oral or nasal corticosteroids, each patient should be titrated to the lowest effective dose. Monitor the severity of the pediatric patient as usual. Generally, taking the smallest dose is effective and in the shortest time to minimize unwanted effects.
Effects on Ability to Drive and Use Machines: Does not affect the ability to drive and operate the machines.