Hypersensitivity to any dihydropyridine or any ingredient of the preparation. ZANIDIP is also contraindicated during pregnancy and lactation; in women of childbearing potential unless effective contraception is used. In patients with left ventricular outflow tract obstruction, untreated congestive cardiac failure, unstable angina pectoris, severe renal or hepatic dysfunction or within 1 month of a myocardial infarction.