Pharmahof Glizide Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Thai FDA Category Presentation/Packing

Concise Prescribing Info

Contents

Glipizide

Indications/Uses

Maturity-onset DM (non-insulin dependent or type II DM) uncontrolled by diet alone.

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Dosage/Direction for Use

Initially ½ to 1 tab daily. Max dose: 8 tab daily in 2 divided doses.

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Overdosage

View Pharmahof Glizide overdosage for action to be taken in the event of an overdose.

Administration

Should be taken on an empty stomach: Take 15-30 min before meals.

Contraindications

Hypersensitivity. Type II DM w/ ketoacidosis & type 1 DM.

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Special Precautions

Increased risk of hypoglycemia. Avoid use in diabetics w/ frequent hypoglycemic episodes. Mask most hypoglycemic symptoms. Monitor blood glucose & response; cyclosporine levels; tacrolimus serum conc. Separate administration time w/ cholestyramine. Avoid concurrent use w/ ethanol. Monitor renal function. Renal or hepatic impairment. Not recommended during pregnancy & lactation.

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Use In Pregnancy & Lactation

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Adverse Reactions

GI disturbances eg, nausea, vomiting, heartburn, anorexia, diarrhoea; skin rashes, pruritus, photosensitivity, hypoglycemic coma; other severe effects eg, cholestatic jaundice, leucopenia, thrombocytopenia, agranulocytosis & hemolytic anemia.

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Drug Interactions

Increased hypoglycemic effect w/ anabolic steroids; ACE inhibitors; H₂ antagonists, antacids, oral Na bicarbonate. Increased levels/effects w/ CYP2C8/9 inhibitors eg, delavirdine, fluconazole, gemfibrozil, ketoconazole, nicardipine, NSAIDs, pioglitazone, sulfonamides. Increased serum conc w/ cyclosporine; tacrolimus. Decreased hypoglycemic effect w/ β-blockers; large amount of ethanol; rifampin. Decreased absorption w/ cholestyramine. Decreased levels/effects w/ CYP2C8/9 inducers eg, carbamazepine, phenobarb, phenytoin, rifampin, rifapentine, secobarbital. May cause hyperglycemia w/ corticosteroids.

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Storage

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Description

View Pharmahof Glizide description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Antidiabetic Agents

ATC Classification

A10BB07 - glipizide ; Belongs to the class of sulfonylureas. Used in the treatment of diabetes.

Thai FDA Category

Presentation/Packing

Form

Glizide tab 5 mg

Packing/Price

100 × 15's;5 × 15's

Pharmahof Glizide

glipizide

Manufacturer:

Pharmahof

Distributor:

Pharmahof