

* The drug should be administered at least 1 hour before meal or as directed by physicians.
* The capsule should not be chewed or broken during and before administration.
Dosage in renal impairment: Dosage adjustment does not appear necessary in patients with such impairment.
Dosage in hepatic impairment: Adjust dose to 10-20 mg once daily due to the increasing of bioavailability of the drug in hepatic impairment patients.