Metrolex Adverse Reactions

The adverse effects are taste disorders (unpleasant metallic taste), furred tongue, nausea, vomiting, gastrointestinal disturbance, diarrhea, epigastric distress, abdominal pain, constipation, stomatitis, gastritis, vulvovaginal candidiasis, drowsiness, dizziness, headache, urticaria, angioedema, pruritus, erythema multiforme, flattening of the T-wave in ECG tracings, dry mouth, flushing, fever, transient leukopenia, transient thrombocytopenia, dysuria, cystitis, polyuria, incontinence, urine may be dark or reddish brown in color which result from metabolism of Metronidazole, ataxia, confusion, depression, insomnia, weakness.
Moreover, maybe found anaphylaxis, convulsion and peripheral neuropathy which characterized by weakness and numbness. In this case, the drug should be discontinued. Another adverse effects including encephalopathy presenting as confusion, ataxia, dysarthria, gait impairment, nystagmus, tremor. These symptoms may disappear after discontinuing the drug. Peripheral neuropathy, leukopenia and transient epileptiform seizures have been associated with high doses of Metronidazole or prolonged treatment. Stopping Metronidazole or lowering the dose usually results in complete resolution.
Injection: Other adverse effects: Thrombophlebitis. Breast and colon cancer may be found in patients with Crohn's disease who have been treated with high dosage of Metronidazole for prolonged periods. Patients with Crohn's disease are known to have an increased incidence of gastroinstestinal and certain extraintestinal cancers including breast and colon cancer. Use of Metronidazole must be avoided in patient with Crohn's disease.