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Pregnancy: There are limited data regarding the use of ebastine in pregnant women. Animal studies do not suggest direct or indirect harmful effects in terms of reproduction toxicity. As a precautionary measure it is preferable to avoid the use of ebastine during pregnancy.
Breastfeeding: It is not known whether ebastine is excreted in mother's milk. The high degree of binding to proteins (>97%) of ebastine and its main metabolite, carebastine, suggests that the medication is not excreted in mother's milk. As a precautionary measure it is preferable to avoid the use of ebastine during lactation.
Fertility: There are no fertility data associated with ebastine in humans.
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