Kestine: Dosing, Side Effect & Interaction

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Caution For Usage Storage MIMS Class ATC Classification Thai FDA Category Presentation/Packing Local Product Insert

Concise Prescribing Info

Contents

Ebastine

Indications/Uses

Symptomatic treatment of seasonal & perennial allergic rhinitis associated or not w/ allergic conjunctivitis; idiopathic chronic urticaria.

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Dosage/Direction for Use

Adult & childn >12 yr 10 mg once daily. Severe symptoms May increase dose to 20 mg once daily. Severe hepatic impairment Max dose: 10 mg daily.

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Overdosage

View Kestine overdosage for action to be taken in the event of an overdose.

Administration

May be taken with or without food.

Contraindications

Hypersensitivity.

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Special Precautions

Not to be used in emergency allergy situations. Patients w/ known cardiac risk eg, those w/ prolonged QT interval, hypokalaemia. Concomitant treatment w/ compd increasing QT interval or inhibiting CYP3A4 enzyme eg, azole antifungals (eg, ketoconazole & itraconazole) & macrolide antibiotics (eg, erythromycin). Concomitant use w/ rifampicin. Not to be used by patients w/ hereditary galactose intolerance, Lapp lactase deficiency or poor absorption of glucose or galactose. May affect ability to drive or use machinery in sensitive individuals. Severe hepatic impairment. Avoid use during pregnancy & lactation. Childn <12 yr.

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Use In Pregnancy & Lactation

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Adverse Reactions

Headache. Drowsiness; dry mouth.

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Drug Interactions

Increased QTc interval; plasma levels w/ azole antifungals eg, ketoconazole or itraconazole & macrolide antibiotics eg, erythromycin. Decreased plasma conc w/ rifampicin. Interference w/ skin allergy tests. Increased effects of other antihistamines.

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Caution For Usage

For caution against possible variation of physical aspect of medicine... Click to view Kestine detailed prescribing information

Storage

View Kestine storage conditions for details to ensure optimal shelf-life.

Description

View Kestine description for details of the chemical structure and excipients (inactive components).

Action

View Kestine mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Antihistamines & Antiallergics

ATC Classification

R06AX22 - ebastine ; Belongs to the class of other antihistamines for systemic use.

Thai FDA Category

Presentation/Packing

Form

Kestine FC tab 20 mg

Packing/Price

30's

Kestine

ebastine

Manufacturer:

Industrias Farmacéuticas Almirall

Distributor:

Pacific Healthcare

Marketer:

Pacific Healthcare