Discontinue treatment if shock & anaphylaxis; agranulocytosis, hemolytic anemia, leukopenia & thrombocytopenia; TEN, SJS, erythema multiforme & acute generalized exanthematous pustulosis; acute kidney injury, nephrotic syndrome & interstitial nephritis; congestive cardiac failure; interstitial pneumonia; GI bleeding & perforation; stenosis &/or intestinal obstruction; hepatic function disorder & jaundice; asthmatic attack; aseptic meningitis; rhabdomyolysis occur. W/draw treatment if abnormalities in periodic lab exams (eg, urinalysis, hematological exam, LFTs) of patients on long-term medication are noted. Avoid long-term use; aimless treatment. May mask signs & symptoms of infection. CV thromboembolic events including MI & cerebrovascular disorder. Patients w/ peptic ulcer associated w/ chronic NSAID-analgesics use & currently on misoprostol therapy; cardiac dysfunction; bronchial asthma; ulcerative colitis, Crohn's disease. History of hypersensitivity; peptic ulcers. Avoid concomitant use w/ other anti-inflammatory analgesics. Existing or history of blood disorders; hepatic function disorder; renal impairment. Temporary sterility in women receiving long-term NSAID therapy. Pregnancy. Constriction of foetal ductus arteriosus in pregnant women on 2nd trimester of pregnancy. Limit drug to min effective use in women who are or are possibly pregnant & monitor amniotic fluid vol & constriction of foetal ductus arteriosus w/ consideration to gestational age & duration of administration. Avoid during lactation. Discontinue nursing if drug administration is essential. Low birth wt infants, newborns, infants & toddlers. Childn & adolescents. Elderly. Observe excessive decrease in body temp, collapse, cold limbs especially in elderly w/ high-grade fever or debilitated patients.
Sign Out
Continue with Google
Sign Up With Email
Already a member?
Sign In
