Isoptin SR Dosage/Direction for Use

Adults: 1 tab in the morning, unless otherwise prescribed by the physician. In patients requiring particularly gradual blood pressure-lowering therapy should be initiated with 120 mg (½ tab) of sustained-released Isoptin SR taken in the morning. If required, after about 2 weeks, the dose may be increased up to 2 tabs daily (1 tab in the morning and evening at an interval of approximately 12 hrs).
Patients on long-term treatment should not take >2 tabs daily. Transient dose increase only when directed by the physician.
In patients with impaired hepatic function, the effect of verapamil is intensified and prolonged depending on the severity of the liver disease due to diminished drug metabolism. In these cases, dosage should be adjusted with special care starting with low doses (approximately 30% of the dose given to patients with normal liver function should be administered to severe liver dysfunction patients).
Isoptin SR permits a convenient dosage regimen with the use of fewer tabs and reduction of the dosage interval to once daily-dosage in hypertension.
Administration: The doses of Isoptin SR as prescribed by the physician are to be taken regularly. The tabs are to be swallowed whole with some liquid, preferably with or shortly after meals.