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INOPIN is administered by IV infusion by diluting with suitable intravenous infusion solution e.g., 0.9% sodium chloride injection, 5% dextrose injection prior to administration. INOPIN is inactivated in alkaline solution; therefore it should not be added to 5% sodium bicarbonate or other alkaline diluent solution.
The initial rate is 2 to 5 µg per kg body-weight per minute and gradually increases 5 to 10 μg per kg body-weight per minute according to the patient's blood pressure, cardiac output, and urine output. Up to 20 to 50 µg per kg body-weight per minute may be required in seriously ill patient.
Pediatric population: The safety and efficacy of Dopamine in pediatric patients has not been established.
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