Gabutin Special Precautions

Avoid abrupt withdrawal, may precipitate seizures.
Use cautiously in patients with severe renal dysfunction; male rat studies demonstrated an association with pancreatic adenocarcinoma.
May cause central nervous system depression, which may impair physical or mental abilities.
Patients must be cautioned about performing tasks which require mental alertness (e.g. operating machinery or driving).
Effects with other sedative drugs or ethanol may be potentiated.
Gabapentin is generally not considered effective in the treatment of absence seizures.
Gabapentin can cause severe systemic hypersensitivity reactions such as drug rash with eosinophilia and systemic symptoms (DRESS), anaphylaxis. Patients should be instructed to discontinue Gabapentin and seek immediate medical care should they experience signs or symptoms of them.
Use in Children: Pediatric patients (3-12 years of age) have shown increased incidence of central nervous system-related adverse effects, including emotional ability, hostility, thought disorder, and hyperkinesias.
Safety and efficacy of drug in patients aged less than 3 years old are still unknown.
Use in Pregnancy & Lactation: Gabapentin should be used during pregnancy only if the potential benefit to the mother clearly outweighs the potential risk to the fetus.
Gabapentin should be used in nursing mothers only if the benefits clearly outweigh the risks.