Erimycin For Suspension Dosage/Direction for Use

Mode of Administration: ERIMYCIN FOR SUSPENSION administered by orally, may be administered without regard to meals or may be administered with food to decrease GI upset. Do not give with milk or acidic beverages.
How supplied ERIMYCIN FOR SUSPENION: To make up to volume, add 2/3 marked volume of water, shake the bottle well and then add water to the marked line. The reconstituted suspension should be stored in a refrigerator (2-8°C), and used within 7 days. Shake well before taking each dose.
Dosage: Due to differences in absorption, 400 mg of Erythromycin ethylsuccinate provide 250 mg of Erythromycin activity as the stearate, bases or estolate.
Usual dosage in children: The usual oral dosage of Erythromycin ethylsuccinate in children is 30-50 mg/kg daily in 4 equally divided doses every 6 hours. Maximum dose 3.2 g daily. Erythromycin ethylsuccinate should be administered for at least 10 days for Streptococcal infections.
Indication-specific dosing: See Table 1.

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Usual dosage in adult: The usual adult oral dosage of Erythromycin ethylsuccinate is 400 mg every 6 hours. Dosage may be increased up to 4 g daily according to the severity of the infection. Maximum dose 4 g daily.
Erythromycin ethylsuccinate should be administered for at least 10 days for Streptococcal infections.
Indication-specific dosing: See Table 2.

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Renal impairment: Since renal excretion is not a major route of elimination of Erythromycin and prolongation of serum half-life of the drug is not clinically important. No supplemental dosage necessary in hemo- or peritoneal dialysis or in continuous arteriovenous or venovenous hemofiltration.
Hepatic impairment: No dosage adjustment; use with caution.