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Pregnancy: Category D.
Cytarabine is teratogenic in some animal species. Its should not be used in pregnant women (especially during the first trimester) or in those who may become pregnant, unless the possible benefits outweigh the potential risks. Women who are, or who may become, pregnant during treatment with cytarabine should be informed of the risks. Men and women have to use effective contraception during and up to 6 months after treatment.
Lactation: It is not known whether cytarabine or its metabolite is distributed into breast milk, and it should not be used in mothers who are breastfeeding.
